The SF3B14 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Sf3b6. This antibody recognizes Human, and Mouse antigen. The SF3B14 Antibody has been validated for the following applications: Western Blot.
Description
Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.Will C.L., EMBO J. 20:4536-4546(2001).Lai C.-H., Genome Res. 10:703-713(2000).Zhang Q.-H., Genome Res. 10:1546-1560(2000)